Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca2+ in Neurons and Astroglia

K Zheng, L Bard, JP Reynolds, C King, TP Jensen, AV Gourine, DA Rusakov

Neuron 2015

Zheng et al, Neuron (2015)

Zheng et al demonstrated in Neuron, that mapped basal Ca2+ in neurons and astrocytes with submicron resolution helps to unveil heterogeneous concentration landscapes that depend on age and preceding activity of the bain. Monitoring nanomolar-scale molecular interaction between OGB1 nanomolar sensitivity dye and Ca2+ was performed by Femto2D-Galvo equipped with FLIM module.

Zheng et al, Neuron, 2015

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Tags: neurons